Order NO. C650059
小鼠抗TOP2A 单克隆抗体
| 英文名 | Anti-TOP2A mouse monoclonal antibody | ||
| 相关类别 | IVD抗体原料 | 储存 | 冷冻（-20℃） 参照组件的存储要求 |
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| C650059-0100 | 100UG | 预计7日内发货 |
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| C650059-0500 | 500UG | 预计7日内发货 |
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产品描述
应用
immunohistochemistry：anti-TOP2A mouse monoclonal antibody
组分
1 mg/ml
适用样本
Human
属性
| Background | This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another, thus altering the topology of DNA. Two forms of this enzyme exist as likely products of a gene duplication event. The gene encoding this form, alpha, is localized to chromosome 17 and the beta gene is localized to chromosome 3. The gene encoding this enzyme functions as the target for several anticancer agents and a variety of mutations in this gene have been associated with the development of drug resistance. Reduced activity of this enzyme may also play a role in ataxia-telangiectasia. |
| Product name | Anti-TOP2A mouse monoclonal antibody |
| Description | Mouse monoclonal antibody to TOP2A |
| Host species | Mouse |
| Tested applications | IHC |
| Reactivity | Human |
| Immunogen | Recombinant protein. The exact sequence is proprietary. |
| Clone number | SG201636m |
| Isotype | IgG1 |
| Purification | Protein A/G affinity column |
| Uniprot ID | P11388 |
相关文档
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Sample Application
