网 站
反 馈
网 站
指 南
Order NO. C600170
重组人HCC-1/CCL14
英文名 Recombinant Human Hemofiltrate CC Chemokine-1/CCL14
别名 HCC-1/CCL14, Human
相关类别 趋化因子 储存 冷冻(-20℃)
分子量 Approximately 8.4 kDa, a single non-glycosylated polypeptide chain containing 72 amino acids.    
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
C600170-0002 2 UG 预计5日内发货
加入购物车
C600170-0010 10 UG 咨询
加入购物车
产品描述

概述

Human CCL14 is belonging to the CC chemokine family. It has two isoforms, CCL14a (HCC-1) and CCL14b (HCC-3). The sequence of HCC-3 differs from HCC-1 as follow: 27-27 R→ QTGGKPKVVKIQLKLVG. CCL14 was first isolated from the hemofiltrate of human patients with chronic renal failure. CCL14 promotes chemotaxis of T lymphocytes, monocytes and eosinophils, and inhibits infection of M-tropic human immunodeficiency virus type 1 and is a ligand for CCR1, CCR3 and CCR5. CCL14 is expressed constitutively in several normal tissues: spleen, liver, skeletal and heart muscle, gut, and bone marrow, present at high concentrations in plasma.

使用说明

This material is offered by Sangon Biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE.

属性

Physical Appearance Sterile Filtered White lyophilized (freeze-dried) powder.
Purity > 96 % by SDS-PAGE and HPLC analyses.
Source Escherichia coli.
Biological Activity Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human monocytes is in a concentration of 5.0-20 ng/ml.
Formulation Lyophilized from a 0.2 μm filtered concentrated solution in 20 mM PB, pH 7.4, 100 mM NaCl.
Endotoxin Less than 1EU/μg of rHuHCC-1/CCL14 as determined by LAL method.
Reconstitution We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 C. Further dilutions should be made in appropriate buffered solutions.
AA Sequence TESSSRGPYH PSECCFTYTT YKIPRQRIMD YYETNSQCSK PGIVFITKRG HSVCTNPSDK WVQDYIKDMK EN
相关文档
质量控制相关文件
质量报告 (COA)
输入LOT号       
我的购物车(0) 结算