Order NO. D624432
CCDC112抗原（重组蛋白）
| 英文名 | CCDC112 Antigen (Recombinant Protein) | ||
| 别名 | MBC1 | ||
| 相关类别 | 抗原 | 储存 | 冷冻（-20℃） |
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D624432-0001 | 1 MG | 预计30日内发货 |
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| D624432-0100 | 100 UG | 预计30日内发货 |
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产品描述
概述
Fusion protein corresponding to a region derived from 247-446 amino acids of human CCDC112
属性
| Full name: | coiled-coil domain containing 112 |
| Synonyms: | MBC1 |
| Swissprot: | Q8NEF3 |
| Gene Accession: | BC031242 |
| Gene ID: | 153733 |
| Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE |
| Expression system: | Escherichia coli |
| Tags: | His tag C-Terminus, GST tag N-Terminus |
| Research areas: | Cell Biology |
| Reconstitution: | Reconstitute with sterile distilled water or deionized water to 1 mg/ml |
| Background: | CCDC112 (coiled-coil domain containing 112), also known as MBC1 (mutated in bladder cancer 1), is a 446 amino acid protein. The gene encoding CCDC112 is located on chromosome 5. Due to alternative splicing events, CCDC112 exists as two isoforms. Chromosome 5 comprises about 6% of human genomic DNA and contains 181 million base pairs encoding around 1,000 genes. It is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome. (The background information is obtained from official databases and does not represent the product information.) |
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