Order NO. D262892
产品描述
概述
This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Elevated levels of the encoded protein have been found in virus infections, including COVID-19 (disease caused by SARS-CoV-2).
应用
酶联免疫吸附测定(ELISA),免疫印迹(WB)
属性
保存缓冲液 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
P05231
|
靶点基因 ID |
3569
|
靶点全称 |
interleukin 6
|
靶点别名 |
CDF; HGF; HSF; BSF2; IL-6; BSF-2; IFNB2; IFN-beta-2
|
靶点研究领域 |
Immunology, Neuroscience, Microbiology, Cancer, Metabolism
|
亚型 |
Immunogen-specific rabbit IgG
|