Order NO. D261596
产品描述
概述
This gene is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene.
应用
酶联免疫吸附测定(ELISA),免疫组织化学(IHC)
属性
保存缓冲液 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
Q13620
|
靶点基因 ID |
8450
|
靶点全称 |
cullin 4B
|
靶点别名 |
SFM2; MRXSC; MRXHF2; MRXS15
|
靶点研究领域 |
Cell Biology
|
亚型 |
Immunogen-specific rabbit IgG
|