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Order NO. D224432
兔抗CCDC112多克隆抗体
英文名 Anti-CCDC112 rabbit polyclonal antibody
别名 coiled-coil domain containing 112; MBC1
相关类别 一抗 储存 冷冻(-20℃)
宿主 Rabbit 反应种属 Human, Mouse
克隆类型 rabbit polyclonal 抗原 CCDC112
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D224432-0025 25 ul 现货
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D224432-0100 100 ul 现货
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D224432-0200 200 ul 现货
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产品描述

概述

CCDC112 (coiled-coil domain containing 112), also known as MBC1 (mutated in bladder cancer 1), is a 446 amino acid protein. The gene encoding CCDC112 is located on chromosome 5. Due to alternative splicing events, CCDC112 exists as two isoforms. Chromosome 5 comprises about 6% of human genomic DNA and contains 181 million base pairs encoding around 1,000 genes. It is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.

应用

酶联免疫吸附测定(ELISA),免疫组织化学(IHC)

属性

保存缓冲液 -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
运输条件 2-8°C
靶点 Uniprot 登记号 Q8NEF3
靶点基因 ID 153733
靶点全称 coiled-coil domain containing 112
靶点别名 MBC1
靶点研究领域 Cell Biology
亚型 Immunogen-specific rabbit IgG
相关文档
Sample Application

  • The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using D224432(CCDC112 Antibody) at dilution 1/45, on the right is treated with fusion protein. (Original magnification: ×200)


  • The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using D224432(CCDC112 Antibody) at dilution 1/45, on the right is treated with fusion protein. (Original magnification: ×200)

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