Order NO. D220478
产品描述
概述
The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
应用
酶联免疫吸附测定(ELISA),免疫组织化学(IHC)
属性
保存缓冲液 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
P50416
|
靶点基因 ID |
1374
|
靶点全称 |
carnitine palmitoyltransferase 1A (liver)
|
靶点别名 |
CPT1, CPT1-L, L-CPT1
|
靶点研究领域 |
Metabolism, Cancer, Cardiovascular
|
亚型 |
Immunogen-specific rabbit IgG
|