Order NO. D145061
人TGFB1重组蛋白（hFc tag N-Terminus）
| 英文名 | Human TGFB1 Recombinant protein (hFc tag N-Terminus) | ||
| 别名 | transforming growth factor beta 1; CED; LAP; DPD1; TGFB; IBDIMDE; TGFbeta; TGF-beta1 | ||
| 相关类别 | 抗原 | 储存 | 冷冻（-20℃） |
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D145061-0010 | 10 UG | 预计5日内发货 |
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| D145061-0050 | 50 UG | 现货 |
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| D145061-0100 | 100 UG | 预计5日内发货 |
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产品描述
概述
Fusion protein corresponding to a region derived from 279-359 amino acids of Human TGFB1
属性
| Full name: | transforming growth factor beta 1 |
| Synonyms: | CED; LAP; DPD1; TGFB; IBDIMDE; TGFbeta; TGF-beta1 |
| Swissprot: | P01137 |
| Purity: | >90%, as determined by Coomassie blue stained SDS-PAGE |
| Expression system: | HEK293 |
| Tags: | hFc tag N-Terminus |
| Species: | Human |
| Molecular mass: | The protein has a predicted molecular weight of 38.9 kDa after removal of the signal peptide. |
| Research areas: | Signal Transduction, Cardiovascular, Cancer, Metabolism |
| Background: | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGFB family members. This encoded protein regulates cell proliferation, differentiation and growth, and can modulate expression and activation of other growth factors including interferon gamma and tumor necrosis factor alpha. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease. [provided by RefSeq, Aug 2016] |
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