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Order NO. D120535
兔抗TNFRSF10C多克隆抗体
英文名 Anti-TNFRSF10C rabbit polyclonal antibody
别名 LIT; DCR1; TRID; CD263; TRAILR3; TRAIL-R3; DCR1-TNFR
相关类别 一抗 储存 冷冻(-20℃)
宿主 Rabbit 反应种属 Human
克隆类型 rabbit polyclonal 抗原 TNFRSF10C
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D120535-0025 25 ul 现货
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D120535-0100 100 ul 现货
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D120535-0200 200 ul 现货
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产品描述

概述

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL.

应用

酶联免疫吸附测定(ELISA),免疫组织化学(IHC)

属性

保存缓冲液 -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
运输条件 2-8°C
靶点 Uniprot 登记号 O14798
靶点基因 ID 8794
靶点全称 tumor necrosis factor receptor superfamily member 10c
靶点别名 LIT; DCR1; TRID; CD263; TRAILR3; TRAIL-R3; DCR1-TNFR
靶点研究领域 Cancer, Immunology
亚型 Immunogen-specific rabbit IgG
相关文档
Sample Application

  • The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using D120535(TNFRSF10C Antibody) at dilution 1/30. (Original magnification: ×200)
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