Order NO. D120354
产品描述
概述
This gene encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease.
应用
酶联免疫吸附测定(ELISA),免疫组织化学(IHC)
属性
保存缓冲液 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
P07339
|
靶点基因 ID |
1509
|
靶点全称 |
cathepsin D
|
靶点别名 |
CPSD; CLN10; HEL-S-130P
|
靶点研究领域 |
Signal Transduction, Cell Biology, Neuroscience
|
亚型 |
Immunogen-specific rabbit IgG
|