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Order NO. C600230
重组小鼠IL-13
英文名 Recombinant Murine Interleukin-13
别名 IL-13, Murine
相关类别 细胞因子 储存 冷冻(-20℃)
分子量 Approximately 12.3 kDa, a single non-glycosylated polypeptide chain containing 111 amino acids.    
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
C600230-0002 2 UG 预计5日内发货 暂不支持线上订购
C600230-0010 10 UG 无货
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产品描述

概述

Murine Interleukin-13 (IL-13) is expressed by the IL13 gene located on the chromosome 11 and secreted by many cell types, especially T helper type 2 (Th2) cells. Targeted deletion of IL-13 in mice resulted in impaired Th2 cell development and indicated an important role for IL-13 in the expulsion of gastrointestinal parasites. IL-13 has been implicated as a key factor in asthma, allergy, atopy and inflammatory response, establishing the protein as a valuable therapeutic target. Human, mouse and rat IL-3 share low homology, but have cross species activity.

使用说明

This material is offered by Sangon Biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE.

技术规格

Physical Appearance Sterile Filtered White lyophilized (freeze-dried) powder.
Purity > 97 % by SDS-PAGE and HPLC analyses.
Source Escherichia coli.
Biological Activity Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human TF-1 cells is less than 4 ng/ml, corresponding to a specific activity of > 2.5 × 105 IU/mg.
Formulation Lyophilized from a 0.2 μm filtered solution in PBS, pH 7.4.
Endotoxin Less than 1 EU/μg of rMuIL-13 as determined by LAL method.
Reconstitution We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
AA Sequence MPVPRSVSLP LTLKELIEEL SNITQDQTPL CNGSMVWSVD LAAGGFCVAL DSLTNISNCN AIYRTQRILH GLCNRKAPTT VSSLPDTKIE VAHFITKLLS YTKQLFRHGP F
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