Order NO. C520815
产品描述
概述
Recombinant Human Cystathionine Gamma-Lyase is produced by our E.coli expression system and the target gene encoding Met1-Ser405 is expressed.
使用说明
This material is offered by Sangon Biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE.
属性
Tag |
None
|
种属 |
Human
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表达系统 |
E.coli
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Accession# |
P32929
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Source |
E.coli
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Formulation_Description |
Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 20% Glycerol, pH 7.4.
|
Storage |
Store at < -20°C, stable for 6 months after receipt.Please minimize freeze-thaw cycles.
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Purity |
Greater than 90% as determined by reducing SDS-PAGE.
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Endotoxin |
Less than 0.1 ng/μg (1 EU/μg) as determined by LAL test.
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Background |
Cystathionine Gamma-Lyase (CTH) belongs to the trans-sulfuration enzymes family. CTH exists as a homotetramer and interacts with CALM in a calcium-dependent manner. CTH breaks down cystathionine into cysteine, ammonia and 2-oxobutanoate. CTH catalyzes the last step in the trans-sulfuration pathway from methionine to cysteine and has broad substrate specificity. Defects in CTH will lead to cystathioninuria, which is an autosomal recessive phenotype characterized by abnormal accumulation of plasma cystathionine.
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