Order NO. D624719
POR抗原（重组蛋白）
| 英文名 | POR Antigen (Recombinant Protein) | ||
| 别名 | CPR; CYPOR; P450R | ||
| 相关类别 | 抗原 | 储存 | 冷冻（-20℃） |
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D624719-0001 | 1 MG | 预计30日内发货 |
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| D624719-0100 | 100 UG | 预计30日内发货 |
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产品描述
概述
Fusion protein corresponding to a region derived from 478-677 amino acids of human POR
属性
| Full name: | cytochrome p450 oxidoreductase |
| Synonyms: | CPR; CYPOR; P450R |
| Swissprot: | P16435 |
| Gene Accession: | BC034277 |
| Gene ID: | 5447 |
| Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE |
| Expression system: | Escherichia coli |
| Tags: | His tag C-Terminus, GST tag N-Terminus |
| Research areas: | Metabolism, Cardiovascular |
| Reconstitution: | Reconstitute with sterile distilled water or deionized water to 1 mg/ml |
| Background: | This gene encodes an endoplasmic reticulum membrane oxidoreductase that is essential for multiple metabolic processes, including reactions catalyzed by cytochrome P450 proteins for metabolism of steroid hormones, drugs and xenobiotics. The encoded protein has a flavin adenine dinucleotide (FAD)-binding domain and a flavodoxin-like domain which bind two cofactors, FAD and FMN, that allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene cause a complex set of disorders, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome, that resemble those caused by defects in steroid metabolizing enzymes such as aromatase, 21-hydroxylase, and 17 alpha-hydroxylase. [provided by RefSeq, Aug 2020] (The background information is obtained from official databases and does not represent the product information.) |
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