Order NO. D624072
XPA抗原（重组蛋白）
| 英文名 | XPA Antigen (Recombinant Protein) | ||
| 别名 | XPA, DNA damage recognition and repair factor; XP1; XPAC | ||
| 相关类别 | 抗原 | 储存 | 冷冻（-20℃） |
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D624072-0001 | 1 MG | 预计30日内发货 |
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| D624072-0100 | 100 UG | 预计30日内发货 |
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产品描述
概述
Fusion protein corresponding to a region derived from 1-273 amino acids of human XPA
属性
| Full name: | XPA, DNA damage recognition and repair factor |
| Synonyms: | XP1; XPAC |
| Swissprot: | P23025 |
| Gene Accession: | BC014965 |
| Gene ID: | 7507 |
| Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE |
| Expression system: | Escherichia coli |
| Tags: | His tag C-Terminus, GST tag N-Terminus |
| Research areas: | Epigenetics and Nuclear Signaling |
| Reconstitution: | Reconstitute with sterile distilled water or deionized water to 1 mg/ml |
| Background: | This gene encodes a zinc finger protein plays a central role in nucleotide excision repair (NER), a specialized type of DNA repair. NER is responsible for repair of UV radiation-induced photoproducts and DNA adducts induced by chemical carcinogens and chemotherapeutic drugs. The encoded protein interacts with DNA and several NER proteins, acting as a scaffold to assemble the NER incision complex at sites of DNA damage. Mutations in this gene cause Xeroderma pigmentosum complementation group A (XP-A), an autosomal recessive skin disorder featuring hypersensitivity to sunlight and increased risk for skin cancer. [provided by RefSeq, Aug 2017] (The background information is obtained from official databases and does not represent the product information.) |
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