Order NO. D623694
CBWD1抗原（重组蛋白）
| 英文名 | CBWD1 Antigen (Recombinant Protein) | ||
| 别名 | COBP | ||
| 相关类别 | 抗原 | 储存 | 冷冻（-20℃） |
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D623694-0001 | 1 MG | 预计30日内发货 |
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| D623694-0100 | 100 UG | 预计30日内发货 |
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产品描述
概述
Fusion protein corresponding to a region derived from 196-395 amino acids of human ZNG1A
属性
| Full name: | Zn regulated GTPase metalloprotein activator 1A |
| Synonyms: | COBP; CBWD1 |
| Swissprot: | Q9BRT8 |
| Gene Accession: | BC132759 |
| Gene ID: | 55871 |
| Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE |
| Expression system: | Escherichia coli |
| Tags: | His tag C-Terminus, GST tag N-Terminus |
| Research areas: | Cell Biology, Neuroscience |
| Reconstitution: | Reconstitute with sterile distilled water or deionized water to 1 mg/ml |
| Background: | Zinc chaperone that directly transfers zinc cofactor to target metalloproteins, thereby activating them. Catalyzes zinc insertion into the active site of methionine aminopeptidase METAP1, which function to cleave the initiator methionine from polypeptides during or after protein translation. Mechanistically, the N-terminal psi-PxLVp motif binds to the C6H2-type zinc finger of inactive form of METAP1. After formation of the docked complex, zinc is transferred from the CXCC motif in the GTPase domain of ZNG1A to the zinc binding site in the peptidase domain of METAP1 in a process requiring GTP hydrolysis. GTP/GDP exchange is required for release of active METAP1. Predicted to enable ATP binding activity. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022] (The background information is obtained from official databases and does not represent the product information.) |
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