Order NO. D622929
NR1I2抗原（重组蛋白）
| 英文名 | NR1I2 Antigen (Recombinant Protein) | ||
| 别名 | nuclear receptor subfamily 1 group I member 2; BXR; PAR; PRR; PXR; SAR; SXR; ONR1; PAR1; PAR2; PARq | ||
| 相关类别 | 抗原 | 储存 | 冷冻（-20℃） |
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D622929-0001 | 1 MG | 预计30日内发货 |
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| D622929-0100 | 100 UG | 预计30日内发货 |
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产品描述
概述
Fusion protein corresponding to a region derived from 205-434 amino acids of human NR1I2
属性
| Full name: | nuclear receptor subfamily 1 group I member 2 |
| Synonyms: | BXR; PAR; PRR; PXR; SAR; SXR; ONR1; PAR1; PAR2; PARq |
| Swissprot: | O75469 |
| Gene Accession: | BC017304 |
| Gene ID: | 8856 |
| Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE |
| Expression system: | Escherichia coli |
| Tags: | His tag C-Terminus, GST tag N-Terminus |
| Research areas: | Signal Transduction, Epigenetics and Nuclear Signaling, Metabolism |
| Reconstitution: | Reconstitute with sterile distilled water or deionized water to 1 mg/ml |
| Background: | This gene product belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand-binding domain and a DNA-binding domain. The encoded protein is a transcriptional regulator of the cytochrome P450 gene CYP3A4, binding to the response element of the CYP3A4 promoter as a heterodimer with the 9-cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4, including dexamethasone and rifampicin. Several alternatively spliced transcripts encoding different isoforms, some of which use non-AUG (CUG) translation initiation codon, have been described for this gene. Additional transcript variants exist, however, they have not been fully characterized. [provided by RefSeq, Jul 2008] (The background information is obtained from official databases and does not represent the product information.) |
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