Order NO. D263669
产品描述
概述
The protein encoded by this gene belongs to the dapper family, characterized by the presence of PDZ-binding motif at the C-terminus. It interacts with, and positively regulates dishevelled-mediated signaling pathways during development. Depletion of this mRNA from xenopus embryos resulted in loss of notochord and head structures, and mice lacking this gene died shortly after birth from severe posterior malformations. Alternatively spliced transcript variants have been found for this gene.
应用
酶联免疫吸附测定(ELISA),免疫组织化学(IHC)
属性
保存缓冲液 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
Q9NYF0
|
靶点基因 ID |
51339
|
靶点全称 |
dishevelled binding antagonist of beta catenin 1
|
靶点别名 |
DPR1; FRODO; HDPR1; DAPPER; THYEX3; DAPPER1
|
靶点研究领域 |
Neuroscience, Signal Transduction
|
亚型 |
Immunogen-specific rabbit IgG
|