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Order NO. D261599
兔抗CYP46A1多克隆抗体
英文名 Anti-CYP46A1 rabbit polyclonal antibody
别名 CP46; CYP46
相关类别 一抗 储存 冷冻(-20℃)
宿主 Rabbit 反应种属 Human, Mouse
克隆类型 rabbit polyclonal 抗原 CYP46A1
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D261599-0025 25 ul 现货
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D261599-0100 100 ul 现货
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D261599-0200 200 ul 现货
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产品描述

概述

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed in the brain, where it converts cholesterol to 24S-hydroxycholesterol. While cholesterol cannot pass the blood-brain barrier, 24S-hydroxycholesterol can be secreted in the brain into the circulation to be returned to the liver for catabolism.

应用

酶联免疫吸附测定(ELISA),免疫印迹(WB),免疫组织化学(IHC)

属性

保存缓冲液 -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
运输条件 2-8°C
靶点 Uniprot 登记号 Q9Y6A2
靶点基因 ID 10858
靶点全称 cytochrome P450 family 46 subfamily A member 1
靶点别名 CP46; CYP46
靶点研究领域 Metabolism, Cancer, Neuroscience
亚型 Immunogen-specific rabbit IgG
相关文档
Sample Application

  • The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using D261599(CYP46A1 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)


  • The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using D261599(CYP46A1 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)


  • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-3: 231, RAMOS, MCF-7 cell lysates, Primary antibody: D261599(CYP46A1 Antibody) at dilution 1/600, Secondary antibody: D110058(HRP-conjugated Goat anti rabbit IgG) at 1/5000 dilution, Exposure time: 10 seconds
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