Order NO. D261142
产品描述
概述
The protein encoded by this gene is involved in diverse aspects of RNA metabolism, including binding and protecting poly(U) termini of nascent RNA polymerase III transcripts from exonuclease digestion, processing 5' and 3' ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. Autoantibodies reacting with this protein are found in the sera of patients with Sjogren syndrome and systemic lupus erythematosus. Alternative promoter usage results in two different transcript variants which encode the same protein.
应用
酶联免疫吸附测定(ELISA),免疫组织化学(IHC)
属性
保存缓冲液 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
P05455
|
靶点基因 ID |
6741
|
靶点全称 |
small RNA binding exonuclease protection factor La
|
靶点别名 |
La; LARP3; La/SSB
|
靶点研究领域 |
Epigenetics and Nuclear Signaling, Immunology
|
亚型 |
Immunogen-specific rabbit IgG
|