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Order NO. D260504
兔抗PPP1R13L多克隆抗体
英文名 Anti-PPP1R13L rabbit polyclonal antibody
别名 RAI, RAI4, IASPP, NKIP1
相关类别 一抗 储存 冷冻(-20℃)
宿主 Rabbit 反应种属 Human, Mouse
克隆类型 rabbit polyclonal 抗原 PPP1R13L
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D260504-0025 25 ul 现货
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D260504-0100 100 ul 现货
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D260504-0200 200 ul 现货
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产品描述

概述

RelA-associated inhibitor is a protein that in humans is encoded by the PPP1R13L gene. Regulator that plays a central role in regulation of apoptosis and transcription via its interaction with NF-kappa-B and p53/TP53 proteins. Blocks transcription of HIV-1 virus by inhibiting the action of both NF-kappa-B and SP1. Also inhibits p53/TP53 function, possibly by preventing the association between p53/TP53 and ASPP1 or ASPP2, and therefore suppressing the subsequent activation of apoptosis. Interacts with RELA NF-kappa-B subunit and with SP1 via its C-terminus part. Interacts with p53/TP53, TP63 and TP73.

应用

酶联免疫吸附测定(ELISA),免疫印迹(WB),免疫组织化学(IHC)

属性

保存缓冲液 -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
运输条件 2-8°C
靶点 Uniprot 登记号 Q8WUF5
靶点基因 ID 10848
靶点全称 protein phosphatase 1, regulatory subunit 13 like
靶点别名 RAI, RAI4, IASPP, NKIP1
靶点研究领域 Epigenetics and Nuclear Signaling, Cancer
亚型 Immunogen-specific rabbit IgG
相关文档
Sample Application

  • The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using D260504(PPP1R13L Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)


  • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using D260504(PPP1R13L Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)


  • Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane 1-2: MCF7 cells, hela cells, Primary antibody: D260504(PPP1R13L Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds
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