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Order NO. D221057
兔抗BDNF多克隆抗体
英文名 Anti-BDNF rabbit polyclonal antibody
别名 brain derived neurotrophic factor; ANON2; BULN2
相关类别 一抗 储存 冷冻(-20℃)
宿主 Rabbit 反应种属 Human, Mouse, Rat
标记物 Unconjugate 克隆类型 rabbit polyclonal
抗原 BDNF    
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D221057-0025 25 ul 现货
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D221057-0100 100 ul 现货
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D221057-0200 200 ul 现货
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技术规格

Background: BDNF is a member of the family of neurotrophic factors. It was first explored and purified from pig brain in 1982, and other members of the neurotrophin family were successively discovered. BDNF is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression of BDNF is reduced in both Alzheimer's and Huntington disease patients. It participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. It also plays a role in the regulation of stress response and in the biology of mood disorders. The BDNF gene is rather complex in its structure and it can express four different mRNA isoforms by alternative splicing, producing 28-37 kDa proteins.
Applications: ELISA, WB, IHC
Name of antibody: BDNF
Immunogen: Fusion protein of human BDNF
Full name: brain derived neurotrophic factor
Synonyms: ANON2; BULN2
SwissProt: P23560
ELISA Recommended dilution: 5000-10000
IHC positive control: Human brain and Human liver cancer
IHC Recommend dilution: 50-100
WB Predicted band size: 28 kDa
WB Positive control: A549 cell lysate
WB Recommended dilution: 500-2000
相关文档
Sample Application

  • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using D221057(BDNF Antibody) at dilution 1/65, on the right is treated with fusion protein. (Original magnification: ×200)


  • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using D221057(BDNF Antibody) at dilution 1/65, on the right is treated with fusion protein. (Original magnification: ×200)


  • Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane: A549 cell lysate, Primary antibody: D221057(BDNF Antibody) at dilution 1/900, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 3 minutes
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