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Order NO. D220518
英文名 Anti-CYP1A1 rabbit polyclonal antibody
别名 AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX
相关类别 一抗 储存 冷冻(-20℃)
宿主 Rabbit 反应种属 Human, Mouse, Rat
标记物 Unconjugate 克隆类型 rabbit polyclonal
抗原 CYP1A1    
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D220518-0025 25 ul 现货
D220518-0100 100 ul 现货
D220518-0200 200 ul 现货


Background: This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15.
Applications: ELISA, WB, IHC
Name of antibody: CYP1A1
Immunogen: Fusion protein of human CYP1A1
Full name: cytochrome P450, family 1, subfamily A, polypeptide 1
Synonyms: AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX
SwissProt: P04798
ELISA Recommended dilution: 1000-5000
IHC positive control: Human liver cancer
IHC Recommend dilution: 25-100
WB Predicted band size: 58 kDa
WB Positive control: Mouse liver tissue
WB Recommended dilution: 500-2000
Sample Application

  • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using D220518(CYP1A1 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)

  • Gel: 10%SDS-PAGE, Lysate: 30 μg, Lane: Mouse liver tissue, Primary antibody: D220518(CYP1A1 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 seconds
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