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Order NO. D220491
英文名 Anti-CUL5 rabbit polyclonal antibody
别名 VACM1, VACM-1
相关类别 一抗 储存 冷冻(-20℃)
宿主 Rabbit 反应种属 Human, Mouse, Rat
标记物 Unconjugate 克隆类型 rabbit polyclonal
抗原 CUL5    
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D220491-0025 25 ul 现货
D220491-0100 100 ul 现货
D220491-0200 200 ul 现货


Background: Core component of multiple SCF-like ECS (Elongin-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAk2. Seems to be involved poteosomal degradation of p53/TP53 stimulated by adenovirus E1B-55 kDa protein. May form a cell surface vasopressin receptor.
Applications: ELISA, IHC
Name of antibody: CUL5
Immunogen: Fusion protein of human CUL5
Full name: cullin 5
Synonyms: VACM1, VACM-1
SwissProt: Q93034
ELISA Recommended dilution: 1000-2000
IHC positive control: Human tonsil
IHC Recommend dilution: 10-50
Sample Application

  • The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using D220491(CUL5 Antibody) at dilution 1/10, on the right is treated with fusion protein. (Original magnification: ×200)

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