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Order NO. D220405
兔抗CEACAM8多克隆抗体
英文名 Anti-CEACAM8 rabbit polyclonal antibody
别名 carcinoembryonic antigen related cell adhesion molecule 8; CD67; CGM6; CD66b; NCA-95
相关类别 一抗 储存 冷冻(-20℃)
宿主 Rabbit 反应种属 Human
标记物 Unconjugate 克隆类型 rabbit polyclonal
抗原 CEACAM8    
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D220405-0025 25 ul 现货
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D220405-0100 100 ul 现货
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D220405-0200 200 ul 现货
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技术规格

Background: Cell surface glycoprotein that plays a role in cell adhesion in a calcium-independent manner (PubMed:8776764, PubMed:2022629, PubMed:11590190). Mediates heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6 (PubMed:8776764, PubMed:2022629, PubMed:11590190). Heterophilic interaction with CEACAM8 occurs in activated neutrophils (PubMed:8776764). By probing white blood cell cDNA libraries with tumor nonspecific crossreacting antigen, Arakawa et al. (1990) isolated a cDNA encoding CEACAM8, which they called NCA-W272. The deduced 349-amino acid protein contains 11 potential N-glycosylation sites and 4 cysteines expected to form 2 intramolecular disulfide linkages. It also has a signal peptide and several domains similar to those of other CEA family proteins, such as CEACAM1 (109770). Immunoblot analysis showed expression of a 70-kD protein that was reduced to a 37-kD major protein and a 34-kD minor protein in the presence of a glycosylation inhibitor.
Applications: ELISA, WB, IHC
Name of antibody: CEACAM8
Immunogen: Fusion protein of human CEACAM8
Full name: CEA cell adhesion molecule 8
Synonyms: CD67; CGM6; CD66b; NCA-95
SwissProt: P31997
ELISA Recommended dilution: 5000-10000
IHC positive control: Human cervical cancer and Human tonsil
IHC Recommend dilution: 50-100
WB Predicted band size: 38 kDa
WB Positive control: A431 and HepG2 cell lysates
WB Recommended dilution: 200-1000
相关文档
Sample Application

  • The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using D220405(CEACAM8 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200)


  • The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using D220405(CEACAM8 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200)


  • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: A431 and HepG2 cell lysates, Primary antibody: D220405(CEACAM8 Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 2 minutes
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