Order NO. D122942
产品描述
概述
This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins.
应用
酶联免疫吸附测定(ELISA),免疫组织化学(IHC)
属性
保存缓冲液 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
Q96CV9
|
靶点基因 ID |
10133
|
靶点全称 |
optineurin
|
靶点别名 |
NRP; FIP2; HIP7; HYPL; ALS12; GLC1E; TFIIIA-INTP
|
靶点研究领域 |
Signal Transduction, Neuroscience, Immunology
|
亚型 |
Immunogen-specific rabbit IgG
|