Order NO. D122872
兔抗EGLN1多克隆抗体
| 英文名 | Anti-EGLN1 rabbit polyclonal antibody | ||
| 别名 | HPH2; PHD2; SM20; ECYT3; HPH-2; HIFPH2; ZMYND6; C1orf12; HIF-PH2 | ||
| 相关类别 | 一抗 | 储存 | 冷冻（-20℃） |
| 宿主 | Rabbit | 反应种属 | Human, Mouse, Rat |
| 克隆类型 | rabbit polyclonal | 抗原 | EGLN1 |
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D122872-0025 | 25 ul | 现货 |
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| D122872-0100 | 100 ul | 现货 |
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| D122872-0200 | 200 ul | 现货 |
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产品描述
概述
The protein encoded by this gene catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. HIF is a transcriptional complex that plays a central role in mammalian oxygen homeostasis. This protein functions as a cellular oxygen sensor, and under normal oxygen concentration, modification by prolyl hydroxylation is a key regulatory event that targets HIF subunits for proteasomal destruction via the von Hippel-Lindau ubiquitylation complex. Mutations in this gene are associated with erythrocytosis familial type 3 (ECYT3).
应用
酶联免疫吸附测定（ELISA），免疫组织化学（IHC）
属性
| 保存缓冲液 | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| 运输条件 | 2-8°C |
| 靶点 Uniprot 登记号 | Q9GZT9 |
| 靶点基因 ID | 54583 |
| 靶点全称 | egl-9 family hypoxia inducible factor 1 |
| 靶点别名 | HPH2; PHD2; SM20; ECYT3; HALAH; HPH-2; HIFPH2; ZMYND6; C1orf12; HIF-PH2 |
| 靶点研究领域 | Cardiovascular, Cancer, Metabolism |
| 亚型 | Immunogen-specific rabbit IgG |
相关文档
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Sample Application
