Order NO. D122769
产品描述
概述
This gene encodes a type I transmembrane protein and member of the immunoglobulin superfamily of cell adhesion molecules. The encoded protein localizes to adherens junctions in pancreatic beta cells and regulates insulin secretion. Autoantibodies against the encoded protein have been detected in serum from patients with type 1 diabetes. This gene may also play a role in glomerular development and decreased expression of this gene has been observed in human glomerular diseases. This gene and the related opposite-strand gene nephrin (GeneID: 527362) are regulated by a bidirectional promoter.
应用
酶联免疫吸附测定(ELISA),免疫印迹(WB)
属性
保存缓冲液 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
Q6UWL6
|
靶点基因 ID |
84063
|
靶点全称 |
kirre like nephrin family adhesion molecule 2
|
靶点别名 |
NLG1; NEPH3; FILTRIN
|
靶点研究领域 |
Cell Biology
|
亚型 |
Immunogen-specific rabbit IgG
|