Order NO. D122050
产品描述
概述
High-affinity self-ligand important in bidirectional T-cell to B-cell stimulation. SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates.
应用
酶联免疫吸附测定(ELISA),免疫印迹(WB)
属性
保存缓冲液 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
Q13291
|
靶点基因 ID |
6504
|
靶点全称 |
signaling lymphocytic activation molecule family member 1
|
靶点别名 |
SLAM; CD150; CDw150
|
靶点研究领域 |
Cardiovascular, Immunology, Stem Cells
|
亚型 |
Immunogen-specific rabbit IgG
|