Order NO. D120874
产品描述
概述
The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene.
应用
酶联免疫吸附测定(ELISA),免疫组织化学(IHC)
属性
保存缓冲液 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
Q15306
|
靶点基因 ID |
3662
|
靶点全称 |
interferon regulatory factor 4
|
靶点别名 |
MUM1; LSIRF; SHEP8; NF-EM5
|
靶点研究领域 |
Epigenetics and Nuclear Signaling, Cancer
|
亚型 |
Immunogen-specific rabbit IgG
|