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Order NO. D120538
英文名 Anti-DDB2 rabbit polyclonal antibody
相关类别 一抗 储存 冷冻(-20℃)
宿主 Rabbit 反应种属 Human, Mouse
标记物 Unconjugate 克隆类型 rabbit polyclonal
抗原 DDB2    
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D120538-0025 25 ul 现货
D120538-0100 100 ul 现货
D120538-0200 200 ul 现货


Background: This gene encodes a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair, and this complex mediates the ubiquitylation of histones H3 and H4, which facilitates the cellular response to DNA damage. This subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E, a recessive disease that is characterized by an increased sensitivity to UV light and a high predisposition for skin cancer development, in some cases accompanied by neurological abnormalities. Two transcript variants encoding different isoforms have been found for this gene.
Applications: ELISA, IHC
Name of antibody: DDB2
Immunogen: Fusion protein of human DDB2
Full name: damage-specific DNA binding protein 2
Synonyms: XPE; DDBB; UV-DDB2
SwissProt: Q92466
ELISA Recommended dilution: 1000-2000
IHC positive control: Human colorectal cancer
IHC Recommend dilution: 30-150
Sample Application

  • The image is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using D120538(DDB2 Antibody) at dilution 1/40. (Original magnification: ×200)
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