Order NO. D120331
产品描述
概述
Calpain, a heterodimer consisting of a large and a small subunit, is a major intracellular protease, although its function has not been well established. This gene encodes a muscle-specific member of the calpain large subunit family that specifically binds to titin. Mutations in this gene are associated with limb-girdle muscular dystrophies type 2A. Alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms and some variants are ubiquitously expressed.
应用
酶联免疫吸附测定(ELISA),免疫组织化学(IHC)
属性
保存缓冲液 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
P20807
|
靶点基因 ID |
825
|
靶点全称 |
calpain 3
|
靶点别名 |
p94; CANP3; LGMD2; nCL-1; CANPL3; LGMD2A
|
靶点研究领域 |
Signal Transduction, Cell Biology
|
亚型 |
Immunogen-specific rabbit IgG
|