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Order NO. C650021
小鼠抗CD45单克隆抗体
英文名 Anti-CD45 mouse monoclonal antibody
相关类别 IVD抗体原料 最新产品 储存 冷冻(-20℃) 参照组件的存储要求
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
C650021-0100 100UG 预计7日内发货
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C650021-0500 500UG 预计7日内发货
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产品描述

应用

immunohistochemistry:anti-CD45 mouse monoclonal antibody.human tonsil tissue and vermiform appendix tissue.

组分

1 mg/ml

适用样本

Human

属性

Background The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported.
Product name Anti-CD45 mouse monoclonal antibody
Description Mouse monoclonal antibody to CD45
Host species Mouse
Tested applications IHC
Reactivity Human
Immunogen Recombinant protein. The exact sequence is proprietary.
Clone number SG200376m
Isotype IgG2b
Purification Protein A/G affinity column
Uniprot ID P08575
相关文档
Sample Application

  • IHC image of CD45 staining in a formalin fixed, paraffin embedded human tonsil tissue (left) and vermiform appendix tissue (right). The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer for 20 minutes. The tissue section was then incubated with mouse anti-CD45(C650021)antibody overnight at 4℃.HRP-conjugated goat anti-mouse IgG was used as secondary antibody. (Original magnification: 100×).

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