Order NO. C650014
小鼠抗CD8单克隆抗体
| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| C650014-0100 | 100UG | 预计7日内发货 |
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| C650014-0500 | 500UG | 预计7日内发货 |
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产品描述
应用
immunohistochemistry：anti-CD8 mouse monoclonal antibody
组分
1 mg/ml
适用样本
Human
属性
| Background | The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. CD8A gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. The major protein isoforms of this gene differ by the presence or absence of a transmembrane domain and thus differ in being a membrane-anchored or secreted protein. CD8B gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified. |
| Product name | Anti-CD8 mouse monoclonal antibody |
| Description | Mouse monoclonal antibody to CD8 |
| Host species | Mouse |
| Tested applications | ELISA, IHC |
| Reactivity | Human |
| Immunogen | Synthetic peptide. The exact sequence is proprietary. |
| Clone number | 1F1 |
| Isotype | IgG2a |
| Purification | Protein A/G affinity column |
| Uniprot ID | P01732 |
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