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Order NO. C522348
重组人NACHRA5, C-6His, Human Cells
英文名 Recombinant Human Neuronal Acetylcholine Receptor Subunit α-5/NACHRA5 , C-6His, Human Cells
相关类别 其他重组蛋白 储存 冷冻(-20℃)
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
C522348-0010 10 UG 预计10日内发货
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C522348-0050 50 UG 预计10日内发货
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产品描述

概述

Recombinant Human Neuronal Acetylcholine Receptor Subunit α-5/NACHRA5 is produced by our Mammalian expression system and the target gene encoding Arg23-Thr254 is expressed with a 6His tag at the C-terminus.

使用说明

This material is offered by Sangon Biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE.

属性

Tag C-6His
种属 Human
表达系统 Human Cells
Accession# P30532
Source Human Cells
Formulation_Description Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Reconstitution Dissolve the lyophilized protein in distilled water.
Purity Greater than 90% as determined by reducing SDS-PAGE.
Endotoxin Less than 0.1 ng/μg (1 EU/μg) as determined by LAL test.
Background Neuronal Acetylcholine Receptor Subunit α-5 (NACHRA5) is a member of the ligand-gated ion channel family. Neuronal AChR is composed of two different type of subunits: α and non-α. When NACHRA5 binds to acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits, leading to the opening of an ion-conducting channel across the plasma membrane. Genetic variations in NACHRA5 have been related to susceptibility to smoking-related behavioral traits and lung cancer, contributing to the smoking quantitative trait locus 3.
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