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Order NO. C521213
重组人IL-15Rα, C-Fc, Human cells
英文名 Recombinant Human Interleukin-15 Receptor Subunit Alpha , C-Fc, Human cells
相关类别 其他重组蛋白 储存 冷冻(-20℃)
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
C521213-0010 10 UG 现货
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C521213-0050 50 UG 现货
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产品描述

概述

Recombinant Human Interleukin-15 Receptor Subunit Alpha is produced by our Mammalian expression system and the target gene encoding Ile31-Thr205 is expressed with a Fc tag at the C-terminus.

使用说明

This material is offered by Sangon Biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE.

技术规格

Tag C-Fc
种属 Human
表达系统 Human cells
Accession# Q13261
Source Human Cells
Formulation_Description Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Storage Lyophilized protein should be stored at < -20°C, thoμgh stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Reconstitution Dissolve the lyophilized protein in distilled water.
Purity Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin Less than 0.1 ng/μg (1 EU/μg) as determined by LAL test.
Background Interleukin 15 Receptor alpha (IL-15Rα) is a transmembrane glycoprotein that plays a pleiotropic role in immune development and function, including the positive maintenance of lymphocyte homeostasis. IL-15Rα chain can bind soluble IL-15 and “transpresent” cytokine to the cells, allowing them to respond to IL-15. Soluble IL-15Rα can function as a specific high-affinity IL-15 antagonist. The soluble IL-15/IL-15Rα complexes exhibit a strong agonistic activity which is mediated throμgh membrane-bound IL-15 receptor β and γ heterodimers and enables signaling to cells.
Biological_Activity Measured by its ability to block human IL-15-induced proliferation of CTLL 2 mouse cytotoxic T cells. The ED50 for this effect is 0.35-3.5 ng/ml.
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