重组人CD212 , C-Fc, Human cells,Recombinant Human Interleukin-12 Receptor Subunit Beta-1 , C-Fc, Human cells 生命科学产品与技术服务-生工生物工程(上海)股份有限公司

Order NO. C521205

重组人CD212 , C-Fc, Human cells

英文名	Recombinant Human Interleukin-12 Receptor Subunit Beta-1 , C-Fc, Human cells
相关类别	其他重组蛋白	储存	冷冻（-20℃）

编号	包装	库存	目录价（￥）	您的价格（￥）	数量
C521205-0010	10 UG	预计10日内发货
C521205-0050	50 UG	预计10日内发货

产品描述

概述

Recombinant Human Interleukin-12 Receptor Subunit Beta-1 is produced by our Mammalian expression system and the target gene encoding Cys24-Glu540 is expressed with a Fc tag at the C-terminus.

使用说明

This material is offered by Sangon Biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE.

属性

Tag	C-Fc
种属	Human
表达系统	Human cells
Accession#	P42701
Source	Human Cells
Formulation_Description	Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Storage	Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Reconstitution	Dissolve the lyophilized protein in distilled water.
Purity	Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin	Less than 0.1 ng/μg (1 EU/μg) as determined by LAL test.
Background	Interleukin12 receptor subunit beta 1 (IL12RB1) is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. IL12RB1 can spontaneously form homodimers and -oligomers, which are able to bind IL12 with only low affinity. IL12 high affinity receptor complex is composed of two subunits designated IL12RB1 and IL12RB2. While IL12RB1 interacts with the IL-12p40 subunit, IL-12p35 is mainly connecting with IL12RB2. This receptor chain is also responsible for transmitting the IL12 signal into the cell. IL12RB1, to the contrary, is also part of the IL23R, where it interacts with the p40 subunit of IL23. IL12RB1 is expressed in activated T cells, NK cells and B cells.