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Order NO. C520508
重组人CDH3, C-6His, Human Cells
英文名 Recombinant Human Cadherin-3 , C-6His, Human Cells
相关类别 其他重组蛋白 储存 冷冻(-20℃)
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
C520508-0010 10 UG 预计10日内发货
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C520508-0050 50 UG 预计10日内发货
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产品描述

概述

Recombinant Human Cadherin-3 is produced by our Mammalian expression system and the target gene encoding Glu25-Gly654(Val237Met) is expressed with a 6His tag at the C-terminus.

使用说明

This material is offered by Sangon Biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE.

属性

Taq C-6His
种属 Human
表达系统 Human Cells
Accession# P22223
Source Human Cells
Formulation_Description Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Reconstitution Dissolve the lyophilized protein in distilled water.
Purity Greater than 85% as determined by reducing SDS-PAGE.
Endotoxin Less than 0.1 ng/?g (1 EU/?g) as determined by LAL test.
Background Cadherin-3 (CDH3) is a single-pass type I membrane protein that belongs to the cadherin superfamily. CDH3 is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region, and a highly conserved cytoplasmic tail. CDH3 is expressed in some normal epithelial tissues and in some carcinoma cell lines. CDH3 preferentially interacts with themselves in a homophilic manner in connecting cells. CDH3 is involved in loss of heterozygosity events in breast and prostate cancer. Mutations in CDH3 have been associated with congential hypotrichosis with juvenile macular dystrophy.
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