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Order NO. C520506
重组人CDH11, C-Fc-6His, Human cells
英文名 Recombinant Human Cadherin-11 , C-Fc-6His, Human cells
相关类别 其他重组蛋白 储存 冷冻(-20℃)
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
C520506-0010 10 UG 预计10日内发货
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产品描述

概述

Recombinant Human Cadherin-11 is produced by our Mammalian expression system and the target gene encoding Phe23-Thr617 is expressed with a Fc, 6His tag at the C-terminus.

使用说明

This material is offered by Sangon Biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE.

属性

Tag C-Fc-6His
种属 Human
表达系统 Human cells
Accession# Q96CZ9
Source Human Cells
Formulation_Description Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Reconstitution Dissolve the lyophilized protein in distilled water.
Purity Greater than 90% as determined by reducing SDS-PAGE.
Endotoxin Less than 0.1 ng/μg (1 EU/μg) as determined by LAL test.
Background Cadherin-11, also known as OSF-4, Osteoblast cadherin and CDH11, is a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Cadherins interact with themselves in a homophilic manner in connecting cells, may thus contribute to the sorting of heterogeneous cell types. Cadherin-11 contains five cadherin domains and is mainly expressed in brain. Mature cadherin proteins consists of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. It is shown that cadherin-11 is a viable molecular target for therapeutic intervention in Glioblastoma multiforme.
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