Order NO. C520495
产品描述
概述
Recombinant Human Butyrophilin Subfamily 1 Member A1 is produced by our Mammalian expression system and the target gene encoding Ala27-Arg242 is expressed with a 6His tag at the C-terminus.
使用说明
This material is offered by Sangon Biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE.
属性
Tag |
C-6His
|
种属 |
Human
|
表达系统 |
Human cells
|
Accession# |
Q13410
|
Source |
Human Cells
|
Formulation_Description |
Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
|
Storage |
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months.
|
Reconstitution |
Dissolve the lyophilized protein in distilled water.
|
Purity |
Greater than 95% as determined by reducing SDS-PAGE.
|
Endotoxin |
Less than 0.1 ng/μg (1 EU/μg) as determined by LAL test.
|
Background |
Butyrophilin Subfamily 1 Member A1 (BTN1A1) is the major protein associated with fat droplets in the milk. It belongs the immunoglobulin superfamily. BTN1A1 acts as a specific membrane-associated receptor for the association of cytoplasmic droplets with the apical plasma membrane. It is localized to the major histocompatibility complex (MHC) class I region of 6p. It may have arisen relatively recently in evolution by the shuffling of exons between 2 ancestral gene families. It is shown that BTN1A1 inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion.
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