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Order NO. C520330
重组小鼠ADIPOQ , N-6His, E.coli
英文名 Recombinant Mouse Adipocyte Complement-related 30 kDa Protein , N-6His, E.coli
相关类别 其他重组蛋白 储存 冷冻(-20℃)
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
C520330-0010 10 UG 预计10日内发货
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C520330-0050 50 UG 预计10日内发货
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产品描述

概述

Recombinant Mouse Adipocyte Complement-related 30 kDa Protein is produced by our E.coli expression system and the target gene encoding Glu18-Asn247 is expressed with a 6His tag at the N-terminus.

使用说明

This material is offered by Sangon Biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE.

属性

Tag N-6His
种属 Mouse
表达系统 E.coli
Accession# Q60994
Source E.coli
Formulation_Description Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Reconstitution Dissolve the lyophilized protein in distilled water.
Purity Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin Less than 0.1 ng/μg (1 EU/μg) as determined by LAL test.
Background Adiponectin is a secreted protein. It is synthesized exclusively by adipocytes and secreted into plasma. Adiponectin is an important adipokine that is involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Adiponectin Stimulates AMPK phosphorylation and activates in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Adiponectin also antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. It inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. Adiponectin may play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex: LMW, MMW or HMW.
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