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Order NO. C006808
活化醛基型树脂
英文名 Carbohydrate Coupling Resin
相关类别 活化树脂 储存 冷藏(2-8℃)
活化醛基型树脂    
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
C006808-0010 10 ML RESIN 现货
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产品描述

概述

The Carbohydrate Coupling Resin is designed for the simple and efficient coupling of glycoproteins to a solid agarose support through oxidized sugar groups. The resin is ideal for immobilized polyclonal antibodies as these are abundant in carbohydrates in their Fc domain. The location in the Fc domain ensures the antibody’s binding site is orientated away from the resin for optimal binding and reduced steric hindrance. Glycoprotein sugar components are first oxidized with sodium meta-periodate to convert the cis-glycol groups to reactive aldehydes. These aldehydes react spontaneously with the hydrazide group on the Carbohydrate Coupling Resin, forming stable hydrazone bonds. The long spacer arm (23) reduces steric hindrance and ensures greater binding of proteins and antibodies during affinity purification. The generated affinity resin can be reused at least 10 times with no significant loss of activity.

特点

  • Hydrazide activated resin for binding reactive aldehydes. Couple 1~5 mg glycoprotein/ml resin. Long Spacer Arm (23). Gentle coupling conditions. For Immobilizing glycoproteins. Immobilize polyclonal antibodies through their Fc domain for optimal orientation. Immobilize any molecule with oxidized sugars.

组份

10 ml resin

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