概述

Our Boronate Resin is designed for the isolation of ribonucleotide and oligonucleotide RNA.The resin consists of boronic acid covalently linked to a polyacrylamide support that offers simple isolation of small molecular weight compounds that have cis-diol groups. The immobilized boronic acid interacts with the cis-diol groups, found in the sugar portion of nucleotides, forming a reversible five member ring complex. Impurities are washed away and then the complex dissociated by low pH or presence of sorbitol.

特点

• 1.Polyacrylamide gel 2.>1.2meq/g boronate load capacity 3.>130μmol sorbitol/ml gel binding capacity 4.6,000Da exclusion limit 5.45-90μm wet bead size

应用

The polyacrylamide support excludes >6000 Da molecules from entering the resin bed and therefore is suitable only for small molecules.

组分

10 ml resin