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Order NO. D120008
兔抗PKM多克隆抗体
英文名 Anti-PKM2 rabbit polyclonal antibody
别名 OIP3, PK3, THBP1
相关类别 一抗 储存 冷冻(-20℃)
宿主 Rabbit 反应种属 Human, Mouse, Rat
克隆类型 rabbit polyclonal 抗原 PKM
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D120008-0025 25 ul 现货
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D120008-0100 100 ul 现货
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D120008-0200 200 ul 现货
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产品描述

概述

This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported.

应用

酶联免疫吸附测定(ELISA),免疫印迹(WB),免疫组织化学(IHC)

属性

保存缓冲液 -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
运输条件 2-8°C
靶点 Uniprot 登记号 P14618
靶点基因 ID 5315
靶点全称 pyruvate kinase M1/2
靶点别名 PK3; TCB; p58; OIP3; PKM2; CTHBP; THBP1; HEL-S-30
靶点研究领域 Metabolism, Epigenetics and Nuclear Signaling, Cancer
亚型 Immunogen-specific rabbit IgG
相关文档
Sample Application

  • The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using D120008(PKM Antibody) at dilution 1/50. (Original magnification: ×200)

  • The image is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using D120008(PKM Antibody) at dilution 1/50. (Original magnification: ×200)

  • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-3: 293T, Raji, MCF7 cell lysates, Primary antibody: D120008(PKM Antibody) at dilution 1/1000, Secondary antibody: D110058(HRP-conjugated Goat anti rabbit IgG) at 1/5000 dilution, Exposure time: 30 seconds
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