概述

EndotoxinOUT was designed for the rapid removal of endotoxins and pyrogens (LPS, lipopolysaccharides) from nucleic acid (DNA) samples. EndotoxinOUT is an ideal product for the cleanup of buffers, cell culture media, protein solutions, nucleic acid (DNA) samples and pharmacological components. EndotoxinOUT consists of 6% cross-linked agarose covalently linked to polymyxin B to bind and remove harmful pyrogens from a solution. Polymyxin B is a family, polymyxin B1 and B2, of antibiotics that bind to the negatively charged site of the lipid A portion of the bacterial lipopolysaccharide layer, neutralizing the endotoxic activity. The covalently coupled agarose and polymyxin B is a stable matrix that resists leaching

应用

Application for cleanup of buffers, cell culture media, protein solutions, DNA samples & pharmacological components, rapid 99.95% removal of endotoxins & pyrogens from samples.

组分

10 ml/bottle

属性

Capacity	≥9995 endotoxin units (EU) removed by 1ml resin from 5ml test containing 10,000EU. ≥99.95% removal.
Bead structure	6%cross-linked agarose
Fractionation Range	10-4,000 kDa for proteins